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  Since hormones both stimulate hair growth and cause hairloss, hormonal changes by far have the biggest impact on hairloss. This is the most common cause of thinning which affects both men and women. Men generally have hairloss concentrated in a specific pattern from the front through to the crown. Women tend to have thinning throughout their head without it being in any specific pattern. This type of hairloss is caused by the androgen DHT, or Dihydrotestosterone.

Since everyone has DHT that is produced by their bodies and only some people suffer from hairloss, there has to be another factor involved. This other factor is having follicles that have a greater number of Androgen receptors for the DHT to attach to. This is the component that is inherited through the genes. To date the most effective preventative treatments are anti androgens, drugs that prevent the creation of DHT. In the future gene therapy will one day be able to alter the genes to prevent the follicles from being affected by DHT.